Innovative Journal Journal of Medical Biomedical and Applied Sciences 2277:4939 10 05 “CAROTID INTIMA MEDIA THICKNESS - A PREDICTOR OF CORONARY ARTERY DISEASE: RETROSPECTIVE ANALYSIS” 1 DR. ASHISH SINGHAL DEPARTMENT OF CARDIOLOGY, OXYGEN HOSPITAL ROHTAK, HARYANA, INDIA DR. SURBHI GUPTA DEPARTMENT OF OBSTETRICS AND GYNECOLOGY, PGIMS, ROHTAK, HARYANA, INDIA DR. ANKUR SINGHAL DEPARTMENT OF UROLOGY, PBM HOSPITAL, BIKANER, RAJASTHAN, INDIA DR. AASHIMA ARON DEPARTMENT OF OBSTETRICS AND GYNECOLOGY, PBM HOSPITAL, BIKANER Journal Article https://doi.org/10.15520/ijmhs.v10i03.282 Abstract BACKGROUND Carotid artery intima-media thickness (CIMT) measurement is a non-invasive method to diagnose early atherosclerosis or predict the risk of myocardial infarction and stroke. Increased CIMT in the common carotid segment is accompanied by yearly risk of 0.7%– 2.2% in coronary heart disease, 0.4%–1.8% for stroke and from 1.8% to 3.2% for total cardiovascular disease. The aim of the study is to find the individual predictor role of CIMT in CAD (Coronary artery disease) patients. 100 Cases selected from CAD patients who underwent PTCA and 100 Controls selected with no history of CAD and stroke. CIMT measurements done in all at common carotid artery level. RESULTS Baseline characteristics like mean age, male sex, obesity, dyslipidemia, diabetes, hypertension, smoking and family history were comparable in cases and controls. The mean CIMT was 1.11 mm in the case and 0.87mm in control (P<0.0001). ROC analysis gave us a got optimal cut-off value of 1.0 mm above for which sensitivity, specificity, and positive and negative predictive values for predicting CAD was 73%, 73%, 73%, and 73%, respectively. Linear regression analysis showed a significant correlation between CIMT and presence of CAD with the R = 0.582 (P ≤ 0.001). Multiple logistic regression analysis showed only CIMT correlated (coefficient 8.03) significantly with presence of CAD. 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