Innovative Journal Innovative Journal of Medical and Health Science 2589-9341 10 11 2020 11 5 The Use of Autologous Platelet Rich Plasma as an adjunct for chronically infected wounds in the Orthopedic Patient –A case report of first clinical experience 1 Shiva Chackan Orthopaedic Department, San Fernando Teaching Hospital, Trinidad and Tobago and Department of Clinical Surgical Science, University of the West Indies. St. Augustine, Trinidad and Tobago Shariful Islam Department of General Surgery, San Fernando Teaching Hospital, Trinidad and Tobago and Department of Clinical Surgical Science, University of the West Indies. St. Augustine, Trinidad and Tobago Trevor Seepaul Orthopaedic Department, San Fernando Teaching Hospital, Trinidad and Tobago and Department of Clinical Surgical Science, University of the West Indies. St. Augustine, Trinidad and Tobago Vijay Naraynsingh Department of Clinical Surgical Science, University of the West Indies. St. Augustine, Trinidad and Tobago Journal Article https://doi.org/10.15520/ijmhs.v10i11.3134 Abstract Chronic Orthopaedic infections and the wounds that accompany them make up a large percentage of Orthopaedic complications that are seen in low resource settings such as ours at the San Fernando General Hospital. Autologous Platelet Rich Plasma has shown relatively good results in the treatment of chronic wounds. However, its role in the treatment of chronically infected wounds after the removal of orthopaedic implants is yet to be explored. This case report analyses and examines the rate of healing of a relatively large ulcer post removal of an infected Orthopaedic implant. Following surgical debridement the wound was treated with PRP and this paper represents the first post surgical wound treated with PRP at our tertiary hospital. Anitua, Eduardo, Autologous platelets as a source of proteins for healing and tissue regeneration.” Thrombosis and Haemostasis, 2003 Mehta, Samir, Watson, J Tracy, Platelet Rich Concentrate: Basic Science and Current Clinical Applications, Journal of Orthopaedic Trauma, 2008, 22, 6, 432, 438, 0890-5339, 10.1097/bot.0b013e31817e793f, Ovid Technologies (Wolters Kluwer Health), https://dx.doi.org/10.1097/bot.0b013e31817e793f Carter, M J, Fylling, C P, Parnell, L K, Use of platelet rich plasma gel on wound healing: a systematic review and meta-analysis, Eplasty, 2011 Adler, Stephen C, Kent, Kriston J, Enhancing wound healing with growth factors, Facial Plastic Surgery Clinics of North America, 2002, 10, 2, 129, 146, 1064-7406, 10.1016/s1064-7406(02)00005-6, Elsevier BV, https://dx.doi.org/10.1016/s1064-7406(02)00005-6 Suthar, Manish, Gupta, Saniya, Bukhari, Suhail, Ponemone, Venkatesh, Treatment of chronic non-healing ulcers using autologous platelet rich plasma: a case series, Journal of Biomedical Science, 2017, 24, 1, 1423-0127, 10.1186/s12929-017-0324-1, Springer Science and Business Media LLC, https://dx.doi.org/10.1186/s12929-017-0324-1 Lacci, M K, Dardik, A, Platelet-rich plasma: support for its use in wound healing, Yale J Biol Med, 2010, 2844688, 2844688 Molloy, Timothy, Wang, Yao, Murrell, George A C, The Roles of Growth Factors in Tendon and Ligament Healing, Sports Medicine, 2003, 33, 5, 381, 394, 0112-1642, 10.2165/00007256-200333050-00004, Springer Science and Business Media LLC, https://dx.doi.org/10.2165/00007256-200333050-00004 Andia, Isabel, Abate, Michele, Platelet-rich plasma: underlying biology and clinical correlates, Regenerative Medicine, 2013, 8, 5, 645, 658, 1746-0751, 1746-076X, 10.2217/rme.13.59, Future Medicine Ltd, https://dx.doi.org/10.2217/rme.13.59 Martinez-Zapata, Maria, José, Autologous platelet-Rich plasma for treating chronic wounds, Cochrane Database of Systematic Reviews, 2012 Smith, Simon E., Roukis, Thomas S., Bone and Wound Healing Augmentation with Platelet-Rich Plasma, Clinics in Podiatric Medicine and Surgery, 2009, 26, 4, 559, 588, 0891-8422, 10.1016/j.cpm.2009.07.002, Elsevier BV, https://dx.doi.org/10.1016/j.cpm.2009.07.002