A Comparative Study Following Single-Dose Versus Three-Dose Perioperative Antimicrobial Prophylaxis In Clean Elective Surgical Cases

Cite this:
[1]
B. R. Sunil Basukala, “A Comparative Study Following Single-Dose Versus Three-Dose Perioperative Antimicrobial Prophylaxis In Clean Elective Surgical Cases”, ijmhs, vol. 5, no. 2, pp. 42–45, Apr. 2015.
© 2022 Interactive Protocols
RIGHTS & PERMISSIONS
Article Views
230
Altmetric
1
Citations
-
LEARN ABOUT THESE METRICS
   PDF  

Abstract

Background: Appropriate antibiotic prophylaxis in surgery is directed towards the most likely pathogens encountered during the surgical procedure. The type of operative procedure is helpful in deciding the appropriate antibiotic spectrum.

Aim & objective: Evaluate and compare the outcomes following single-dose versus three-dose perioperative antimicrobial prophylaxis in clean elective surgical cases.

Methodology: 200 patients undergoing clean elective surgery were divided in two groups based on odd and even registration numbers.The studyGroup I received a single dose of injection cefotaxime (30 mg/kg/dose) half an hour prior to start of surgery.Group II received three doses of antimicrobial agent and the follow up was done till 1 month following surgery for Surgical Site Infection. Data were analyzed using Chi square test and Fischer exact test in SPSS version 20.

Results: Out of 100 patients included in the study in each group, 3 patients (3%) in single dose group and 4 patients (4%) in three dose group developed SSI within 30 days of surgery.

Discussion: Indiscriminate use of antibiotics is discouraged because it may lead to the emergence of antibiotic-resistant strains of organisms or serious hypersensitivity reactions.

KEYWORDS:

 Special Issue

Article Metrics Graph

Chart Graph | Range Graph

Content

Section

Source

License

All paper submissions must carry the following duly signed by all the authors:
“I certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.”