The Association between Metabolic Syndrome Combined with Fatty Liver Disease and Gallstone Disease—Data Analysis of Health Examinations

  • Wei-Cheng Shiao, Jau-Nan Lin, Chao-Hsi Chia-Hsin Lai, Szu-Mei Hsiao Pi-Li Lin, Tsan Yang
Cite this:
[1]
W.-C. S. . J.-N. L. C.-H. C.-H. L. S.-M. H. Pi-Li Lin, Tsan Yang, “The Association between Metabolic Syndrome Combined with Fatty Liver Disease and Gallstone Disease—Data Analysis of Health Examinations”, ijmhs, vol. 6, no. 3, Jun. 2016.
© 2022 Interactive Protocols
RIGHTS & PERMISSIONS
Article Views
247
Altmetric
1
Citations
-
LEARN ABOUT THESE METRICS
   PDF  

Abstract

Background：In Taiwan, the prevalence rate of gallstone disease (GD) is estimated to be 5%-10% among adults. Several reports have suggested that females and old age individuals have a higher prevalence rate of GD. In addition, hyperglycemia, dyslipidemia and obesity, which are common features of metabolic syndrome, are risk factors for GD. Few studies have examined the relationship between metabolic syndrome combined with fatty liver disease and gallstone disease. Purpose: This study aimed to investigate the relationship between metabolic syndrome combined with fatty liver disease and gallstone disease. Methods: This study applied cross-sectional data analysis. Participants received physical examination at a local hospital in Kaohsiung, Taiwan, from 2011 to 2014. Fatty liver disease and gallstone disease were diagnosed by a gastroenterologist with abdominal ultrasonography. The metabolic syndrome was defined according to the standards set by Health Promotion Administration, Ministry of Health and Welfare, in 2007. Physical examination and blood test results were employed to evaluate the prevalence rate and risk factors of gallstone disease.

Results: The results indicated that prevalence rate of GD was 5%. GD had a significantly higher prevalence among participants aged 40 years and older than those under 40 years old. GD prevalence rate was higher among participants with abnormalities associated with metabolic syndrome and its components than healthy participants. GD prevalence rate was significantly higher among participants with mild or moderate fatty liver combined with metabolic syndrome than those without the metabolic syndrome or with a different degree of fatty liver disease. Participants aged 40 years and older had a 2.88-fold higher risk of getting GD than those who were under 40 years old. The risk of GD increased 1.70-fold in participants with mild fatty liver disease combined with metabolic syndrome and 1.32-fold in participants with moderate fatty liver disease combined with metabolic syndrome. Conclusion: Prevalence and risk of GD is significantly higher in participants with metabolic syndrome. Awareness of GD prevalence rate and risk factors can facilitate effective GD prevention.

KEYWORDS:

 Special Issue

Article Metrics Graph

Chart Graph | Range Graph

Content

Section

Source

License

All paper submissions must carry the following duly signed by all the authors:
“I certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.”