The risk factors that contribute to the etiology of non-syndromic cleft lip with or without cleft palate (CL/P) in the J&K population

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M. S. M. S. B. A. M. I. Azhar Khan, Azhar Hashmi, “The risk factors that contribute to the etiology of non-syndromic cleft lip with or without cleft palate (CL/P) in the J&K population”, ijmhs, vol. 6, no. 6, Dec. 2016.
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Abstract

Cleft lip and palate (CLP) are most common defects of the orofacial complex. A cleft lip or palate happens when the structures that form the upper lip or palate fail to fuse together properly when a baby is developing in the womb. In most cases the exact cause is unknown, but it's thought to be a combination of genetic (internal) and environmental (external) factors. It can occur as a part of syndrome or more commonly as isolated non syndromic pattern. In this study, we tried to find the relationship of external risk factors such as parental age, consangious marriage, socioeconomic status, family history , drug history with the formation of CLP . In addition we also tried to find the relationship of mother’s folic acid level with the development of CLP.

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