Association of lichen planus with metabolic syndrome – a case control study in a tertiary care centre

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Nishant Saurabh Saxena, Nimisha Saxena, and Harsh Sharma, “Association of lichen planus with metabolic syndrome – a case control study in a tertiary care centre”, ijmhs, vol. 11, no. 03 (May - June), pp. 1695–1701, May 2021.
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Abstract

Background: Lichen planus is an inflammatory papulosquamous disease
which affects skin and mucous membrane and cause metabolic
derangements.
Methods: This is an hospital based case control study during a span of 2
year (Jan2018-Dec 2019) which includes 60 cases of lichen planus and
60 age and sex matched controls. Relevant clinical history and physical
examination was done and collaborated with blood investigations.
Diagnosis was made based on IDF criteria.
Results: No significant association can be established between lichen
planus and metabolic syndrome ( p=0.278) Although prevalence of
hypertension was higher in cases as compared to controls (36% vs. 26%,
p=0.027) , TG levels (12% vs. 6%, p=0.030 and low HDLC levels (47%
vs. 33%, p=0.039). No significant association was established between
FBS and waist circumference with lichen planus.
Conclusions: Although no significant association can be established
between lichen planus and metabolic syndrome but its components such
as hypertension ,TG and HDLC were found to be associated with LP as
per the study .Therefore screening of these parameters in LP patients is
necessary to avoid future complications in these patients.
Keywords: Lichen planus, Metabolic syndrome, Hypertension, Triglyceride

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