PERSISTENT HYPERINSULINAEMIC HYPOGLYCAEMIA IN A SIX-WEEK OLD NIGERIAN BOY: CLINICAL PRESENTATION AND MANAGEMENT CHALLENGES IN A DEVELOPING COUNTRY.

Cite this:
[1]
A. N. O. M. M. O. Louis C. Onyiriuka, “PERSISTENT HYPERINSULINAEMIC HYPOGLYCAEMIA IN A SIX-WEEK OLD NIGERIAN BOY: CLINICAL PRESENTATION AND MANAGEMENT CHALLENGES IN A DEVELOPING COUNTRY”., ijmhs, vol. 1, no. 1, Oct. 2013.
© 2022 Interactive Protocols
RIGHTS & PERMISSIONS
Article Views
202
Altmetric
1
Citations
-
LEARN ABOUT THESE METRICS
   PDF  

Abstract

This paper reported a case of a six-week old Nigeria boy with persistent hyperinsulinaemic hypoglycaemia of infancy (PHHI) who presented with typical clinical and laboratory features and in whom some management challenges commonly seen in developing countries were encountered. The clinical diagnostic features included: at the time of hypoglycaemia (blood glucose level 1.6 mmol/L), serum insulin level of 6 mU/ml; absence of ketonuria and acidosis; and elevated level of serum C-peptide and a high glucose infusion rate (12 mg/kg/day) with persistence of the hypoglycaemia. Management challenges encountered included non-availablity of a long-acting somatostatin analog (octereotide) for treatment, lack of investigative facility for distingiuishing between diffuse beta-cell hyperplasia and focal beta-cell microadenoma, paucity of surgical expertise for pancreatectomy and lack of fund to pay for medical treatment abroad in the event of referral.

KEYWORDS:

 Special Issue

Article Metrics Graph

Chart Graph | Range Graph

Content

Section

Source

License

All paper submissions must carry the following duly signed by all the authors:
“I certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.”