K.Jyothsna, D.Nagaveni, M.Rama Rao, G.Vijaya Lakshmi
Introduction: Antimicrobial resistance(AMR) has emerged as a major public health problem all over the world. Infections caused by resistant microbes fail to respond to treatment, resulting in prolonged illness and greater risk of death. Treatment failures also lead to longer periods of infectivity, with increased numbers of infected people moving in the community. This in turn exposes the general population to the risk of contracting a resistant strain of microorganisms. Thus antibiotic susceptibility patterns were conducted. Material And Methods: One hundred and eighty four samples obtained from sputum, throat, blood, urine, pus, stool and ear swab. Among them 84 were reported the presence of bacterial infection. Culture examination was carried out using blood agar and MacConkey’s medium, followed by inoculation by four flame streak method. Antibiotic susceptibility was confirmed by disk diffusion technique on Muller-Hinton medium, performed according to the Clinical Laboratory Standard Institute (CLSI) guidelines. Results And Discussion: E.coli and Klebsiella were completely(100%) susceptible amikacin and levofloxacin. Thus Levofloxacin, much safer drug was used as first line drug. The alternative drug was amikacin, because of its adverse effects. Second line drug was ciprofloxacin. Cefotaxime can be use for bacteremias. Urinary tract infections were caused by E.coli, Klebsiella. Thus were susceptable to Nitrofurantoin completely. Conclusion: Thus antibiotic sensitivity pattern is intended to provide, clinicians and surgeons, valuable information upon which empiric antimicrobial therapy of infection can be predicted.
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