An analytical study comparing Misoprostol and Oxytocin to prevent postpartum haemorrhage

  • Dr. Sumi Agarwal
  • Dr. Manjusha Agarwal
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D. S. Agarwal and D. M. Agarwal, “An analytical study comparing Misoprostol and Oxytocin to prevent postpartum haemorrhage ”, ijmhs, vol. 11, no. 01 (Jan- Feb), Jan. 2021.
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Abstract

Introduction : The present study was carried out with objectives to see the efficacy of rectal misoprostol in comparison to intramuscular oxytocin in prevention of postpartum haemorrhage in low risk patient.

Methods: Data of 400 randomly selected  obstetric patients who seeked care for delivery at the Obstetrical Units were retrospectively identified. Divided into two groups of A ( Rectal Misoprostol & B  of Oxytocin I.M.

Results: No statistical difference among baseline variables , mean duration of labour. The difference in mean blood loss between rectal misoprostol group and oxytocin group is statistically significant. Blood loss during third stage is found to be more in misoprostol group than oxytocin group.

Conclusion : It is observed that the misoprostol rectally is less effective than intramuscular oxytocin when used as prophylactic uterotonic during the active management of third stage of labour. Third stage blood loss found to be significantly more with misoprostol.

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“I certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.”

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