Case report:Juvenile Amyotrophic lateral sclerosis: classical wine glass sign on MRI

Cite this:
[1]
S. K. P. A. A. Neera Kohli, “Case report:Juvenile Amyotrophic lateral sclerosis: classical wine glass sign on MRI”, ijmhs, vol. 6, no. 2, Mar. 2016.
© 2022 Interactive Protocols
RIGHTS & PERMISSIONS
Article Views
285
Altmetric
1
Citations
-
LEARN ABOUT THESE METRICS
   PDF  

Abstract

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig disease, is a chronic degenerative neurologic disease and is characterized by the selective involvement of the motor system. Usually patients present with upper motor neuron (UMN) and lower motor neuron (LMN) compromise. Degeneration of the UMN in the cerebral cortex is one of the main pathologic changes in ALS. These changes usually affects corticospinal tracts (CST) leading to degeneration of the fibres which show characteristic hyper intensities along the tracts leading to the “wine glass signâ€.  Patients with ALS usually present in the 6th decade of life; presentation in pediatric age in the form of juvenile ALS (JALS) being rare.

KEYWORDS:

 Special Issue

Article Metrics Graph

Chart Graph | Range Graph

Content

Section

Source

License

All paper submissions must carry the following duly signed by all the authors:
“I certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.”