L-Asparginase toxicity profile at a tertiary care hematology centre in kashmir – 10 year experience.

  • Shakeeb Nabi, Syed Nazima, Asif Ahmed, Yasir Bashir, Sajad Geelani Javid Rasool, Nusrat Bashir, Dekyong Angmo
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S. N. S. N. A. A. Y. B. S. G. Javid Rasool, Nusrat Bashir, Dekyong Angmo, “L-Asparginase toxicity profile at a tertiary care hematology centre in kashmir – 10 year experience”., ijmhs, vol. 7, no. 4, Aug. 2017.
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Abstract

Purpose: To study overall incidence of adverse effects, highlight incidence of life threatening complications, identify unusual complication if any and possible measures to prevent them.

Materials and methods: This was a ten year retrospective study where in data related to patients at presentation and data related to complications was taken from regional cancer registry and was compiled.

Conclusion:Asparaginase is aessential  component of acute leukemia  protocols . The ability to rapidly identify and manage asparaginase-associated toxicity will help ensure patients receive the maximal benefit from asparaginase therapy.

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