Perifollicular Blood Flow in Controlled Ovarian Hyperstimulation

Sharad Prabhakar Rao Ingle*, Mahalaxmi Saravanan, Nidhi Sharma, Priya Senthil, Sargunadevi, Neenu Sugesh

Perifollicular Blood Flow in Controlled Ovarian Hyperstimulation

Sharad Prabhakar Rao Ingle*, Mahalaxmi Saravanan, Nidhi Sharma, Priya Senthil, Sargunadevi, Neenu Sugesh

Cite this:

[1]

Sharad Prabhakar Rao Ingle*, Mahalaxmi Saravanan, Nidhi Sharma, Priya Senthil, Sargunadevi, Neenu Sugesh, “Perifollicular Blood Flow in Controlled Ovarian Hyperstimulation”, ijmhs, vol. 10, no. 05, pp. 873–876, May 2020.

RIGHTS & PERMISSIONS

Article Views

233

Altmetric

Citations

LEARN ABOUT THESE METRICS

Abstract

Background: The aim of this study was to investigate the association of perifollicular
blood flow with oocyte quality , metaphase 2 conversion and embryo quality after
controlled ovarian hyperstimulation in antagonist cycles .
Objective: The primary aim was to measure the perifollicular Doppler blood flow
indices in graffian follicle and correlate it with number of mature oocytes retrieved
in women undergoing intracytoplasmic sperm injection (ICSI) in controlled ovarian
hyperstimulation with gonadotropins in antagonist cycles .The secondary aim was to
assess the blastocysts obtained from these oocytes.
Results: Antagonist protocol was used for controlled ovarian stimulation with sequential
gonadotropin protocol . Peripheral Vascularity, pulsatility Index (PI) and
resistive index (RI) of perifollicular perfusion were assessed on day 10 for 65 follicles.
After oocyte retrieval the count of metaphase stage 2 oocytes, and day 5 embryos
obtained were evaluated.
RI and PI indices had a positive correlation with age (p value nonsignificant). Follicles
with 18 mm diameter and >75% of circumferential perfusion (p value= 0.04,
significant ), Follicle with > 75% circumferential vascularity with low PI and RI were
associated with high number of metaphse 2 oocytes (p value significant). Follicles
with >75% of vasculaity with low PI and RI were associated high number of Day 5
blastocyst (p value significant).
Conclusion: In our study, the Doppler indices of perifollicular blood flow provided
a reliable prediction of the number and quality of metaphase 2 oocytes and day 5
embryos. Hence perifollicular blood flow is a simple, non-invasive and economical
marker to predict response to gonadotropins in controlled ovarian hyperstimulation.
Key words: Doppler sonography–Graffian Follicle–Metaphase–oocytes–Blastocyst

Content

Part of special issue:

Innovative Journal of Medical and Health Science

Article Metrics by Journal Systems

Citations not available
Readers 233
Download 125

Altmetric Attention score:

Altmetric badge

Share this article

Source

How to Cite

[1]

Issue Vol. 10 No. 05 (2020): Innovative Journal of Medical and Health Science
Section Research Articles

License

All paper submissions must carry the following duly signed by all the authors:
â€œI certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.â€

Innovative Journal of Medical and Health Sciences

Perifollicular Blood Flow in Controlled Ovarian Hyperstimulation

Article Views

Altmetric

Citations

Abstract

Special Issue

Article Metrics Graph

Content

Section

Source

License