“CAROTID INTIMA MEDIA THICKNESS - A PREDICTOR OF CORONARY ARTERY DISEASE: RETROSPECTIVE ANALYSIS”

DR. ASHISH SINGHAL*, DR. SURBHI GUPTA, DR. ANKUR SINGHAL, DR. AASHIMA ARON

“CAROTID INTIMA MEDIA THICKNESS - A PREDICTOR OF CORONARY ARTERY DISEASE: RETROSPECTIVE ANALYSIS”

DR. ASHISH SINGHAL*, DR. SURBHI GUPTA, DR. ANKUR SINGHAL, DR. AASHIMA ARON

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DR. ASHISH SINGHAL*, DR. SURBHI GUPTA, DR. ANKUR SINGHAL, DR. AASHIMA ARON, “‘CAROTID INTIMA MEDIA THICKNESS - A PREDICTOR OF CORONARY ARTERY DISEASE: RETROSPECTIVE ANALYSIS’”, ijmhs, vol. 10, no. 05, pp. 882–886, May 2020.

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Abstract

BACKGROUND
Carotid artery intima-media thickness (CIMT) measurement is a non-invasive method
to diagnose early atherosclerosis or predict the risk of myocardial infarction and stroke.
Increased CIMT in the common carotid segment is accompanied by yearly risk of
0.7%– 2.2% in coronary heart disease, 0.4%–1.8% for stroke and from 1.8% to 3.2%
for total cardiovascular disease. The aim of the study is to find the individual predictor
role of CIMT in CAD (Coronary artery disease) patients. 100 Cases selected from CAD
patients who underwent PTCA and 100 Controls selected with no history of CAD and
stroke. CIMT measurements done in all at common carotid artery level.
RESULTS
Baseline characteristics like mean age, male sex, obesity, dyslipidemia, diabetes, hypertension,
smoking and family history were comparable in cases and controls. The
mean CIMT was 1.11 mm in the case and 0.87mm in control (P<0.0001). ROC analysis
gave us a got optimal cut-off value of 1.0 mm above for which sensitivity, specificity,
and positive and negative predictive values for predicting CAD was 73%, 73%, 73%,
and 73%, respectively. Linear regression analysis showed a significant correlation between
CIMT and presence of CAD with the R = 0.582 (P 0.001). Multiple logistic
regression analysis showed only CIMT correlated (coefficient 8.03) significantly with
presence of CAD.
CONCLUSION
CIMT independently can predict presence of CAD whether traditional atherosclerotic
risk factors are present or not. Deploying CIMT evaluation in low and intermediate
risk individual(s) to detect subclinical CAD will be a good strategy in resource limited
setting specially where invasive modalities are not easily available.
Key words: CIMT–CAD

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Issue Vol. 10 No. 05 (2020): Innovative Journal of Medical and Health Science
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Innovative Journal of Medical and Health Sciences

“CAROTID INTIMA MEDIA THICKNESS - A PREDICTOR OF CORONARY ARTERY DISEASE: RETROSPECTIVE ANALYSIS”

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