Introduction: With the increasing number of deaths due to cardiovascular events, there is an urgent need for optimising the risk factors associated with it. The safety and cost effective non-invasive method to assess the blood pressure and modulate the treatment plan accordingly is to utilise the ambulatory blood pressure monitoring and Holter Electrocardiography in daily use in patients with hypertension.
Aim: To examine the functional state of cardiovascular system and possible predictive value of the daily application of the combined method of arterial blood pressure monitoring and ECG monitoring in hypertensive patients at different levels of the disease progression.
Methods and materials: We examined 37 patients with AH without any clinical significant pathology were included in the first group and 32 hypertensive patients with a history of myocardial infarction (MI) in the second group. The average age of participants in this study was 59,02±2,18 years. All patients underwent a comprehensive examination of the functional state of the cardiovascular system using the combined ECG and arterial BP monitoring validated device «CardiosensBP» XAI-MEDICA (Ukraine). The statistical data was processed using «STATISTICA® for Windows 6.0» (StatSoft Inc., #AXXR712D833214FAN5).
Results: The hypertensive state is characterized by an excess of the target values ??of systemic blood pressure: the daily mean values ??of systolic blood pressure (SBP) and diastolic blood pressure (DBP) were higher at 6,93% (P<0,05) and 5,68% (P<0,01) respectively in both groups. Indicators of pressure increase and morning surge(MS) are significant in patients of the second clinical group exclusively SBP, namely: the index of time (IT) - by 24,68% (P<0,01), the index of measurements (IM) - by 16,84% (P<0,05), MS - by 31,98% (P<0,01).
Conclusions: The practice of application of daily arterial blood pressure and ECG monitoring has an important prognostic value in cardiovascular system functional status estimation and also enables the physician in optimising the treatment plan accordingly.
Introduction: With the increasing number of deaths due to cardiovascular events, there is an urgent need for optimising the risk factors associated with it. The safety and cost effective non-invasive method to assess the blood pressure and modulate the treatment plan accordingly is to utilise the ambulatory blood pressure monitoring and Holter Electrocardiography in daily use in patients with hypertension.
Aim: To examine the functional state of cardiovascular system and possible predictive value of the daily application of the combined method of arterial blood pressure monitoring and ECG monitoring in hypertensive patients at different levels of the disease progression.
Methods and materials: We examined 37 patients with AH without any clinical significant pathology were included in the first group and 32 hypertensive patients with a history of myocardial infarction (MI) in the second group. The average age of participants in this study was 59,02±2,18 years. All patients underwent a comprehensive examination of the functional state of the cardiovascular system using the combined ECG and arterial BP monitoring validated device «CardiosensBP» XAI-MEDICA (Ukraine). The statistical data was processed using «STATISTICA® for Windows 6.0» (StatSoft Inc., #AXXR712D833214FAN5).
Results: The hypertensive state is characterized by an excess of the target values ??of systemic blood pressure: the daily mean values ??of systolic blood pressure (SBP) and diastolic blood pressure (DBP) were higher at 6,93% (P<0,05) and 5,68% (P<0,01) respectively in both groups. Indicators of pressure increase and morning surge(MS) are significant in patients of the second clinical group exclusively SBP, namely: the index of time (IT) - by 24,68% (P<0,01), the index of measurements (IM) - by 16,84% (P<0,05), MS - by 31,98% (P<0,01).
Conclusions: The practice of application of daily arterial blood pressure and ECG monitoring has an important prognostic value in cardiovascular system functional status estimation and also enables the physician in optimising the treatment plan accordingly.
- Introduction: Visceral Leishmania represents a challenging diagnosis and treatment because the clinical picture of Visceral Leishmaniasis, so that the treatment outcome is compromised with many factors, thus study try to asses real picture of treatment outcome with determinants.
Objective: To assess treatment outcome and determinant factors among patient with visceral Leishmaniasis in Arba Minch General Hospital Leishmania Research and Treatment Center.
Methods: Institution-based, Cross-sectional, retrospective study was conducted among Leishmaniasis patients in Arba Minch general hospital. Patient charts that have been treated from January 2011-December 2015 were reviewed. A total of 348 charts were selected by Simple Random Sampling technique and included in the study. The data were entered and cleaned using Epi-info version 7.0 and analysis was carried out using SPSS-20 statistical packages. Multi-variate logistic regression analysis was carried out to identify the independent predictors of treatment outcome.
Result: A total of 348 patient's charts were included in the study. The prevalence of poor outcome was found to be 8.6%. The presence of bleeding/Epsitaxis[AOR=5;95% CI:1.3,19.3], tuberculosis[AOR=3.7;95%CI:1.83,6.3], septic syndrome[AOR=4.3;95% CI: 6.1,32], and adverse drug side effect[AOR=4.5;95%CI:2.73,13.6] were the independent predictors of treatment outcome.
Conclusion and recommendation: The prevalence of poor treatment outcome among patients with VL in the study area is high. Concomitant infection; bleeding/Epsitaxis, tuberculosis, septic syndrome and adverse side effect were independently associated with poor treatment outcome. The clinical management of VL in co-infected patients is a major challenge that requires new treatment approaches to improve its outcome.
Introduction: The identification of Obstetric danger signs and its relation with complication during pregnancy would enable the mother , their care provider to seek health care timely, attending the necessary steps to have a safe birth and post-partum. Insufficient knowledge regarding this problem among mothers, families, and birth attendants in developing world is the major attributing predictor for maternal deaths.
Objectives: To assess knowledge, attitude, health–seek behavior and associated factor of danger signs during pregnancy among pregnant mothers attending Antenatal care in Family Guidance Association Clinic, 2016, Hawassa, Ethiopia.
Methods: Institution based cross-sectional study design was conducted from May 05/ 2016 to August 01/2016 G.C. A total of 251 pregnant mothers were included in the study using a single population proportion formula. A systematic random sampling method was used to select study participants from pregnant mothers attending Antenatal care. Data was collected by using structured interviewer administered questionnaire. Data was entered into EPI info version 3.5.1 and exported to SPSS version 21 statistical software package for cleaning, coding and analysis. Descriptive statistics was done to assess basic characteristics. Factors that show association in Bivariable analysis was entered into Multivariable logistic regression model. The strength of statistical association was measured by AOR, 95% confidence intervals, and P-value <0.05 will be considered as significant.
Result: A total of 251 pregnant women were included in the study with a response rate of 100%. The study revealed that 60.6% of participants had heard about obstetric danger signs .The percentage of women who have positive attitude toward seeking medical care and privation obstetric danger sign during pregnancy was 86.9% and 84.5% of the study participants had practice seek medical care when they faced problem.
Conclusion: The knowledge, Attitude and practice of Obstetric danger signs were affected by educational status, occupation, and Null parity. Efforts need focus on availing antenatal care services with appropriate information on danger signs of pregnancy to increase the knowledge of pregnant women about danger signs during pregnancy.
Small bowel obstruction (SBO) is a common clinical condition. The effective management depends on an early and accurate diagnosis. Gall stone ileus is a rare cause of mechanical small bowel obstruction and contributes to 1-4% of all cases of mechanical small bowel obstruction. The incidence is typically seen in elderly females. The diagnosis is often difficult and a previous history of gall stone disease helps in reaching the correct diagnosis. Surgical management is the preferred modality for treatment. We are reporting a case of Gallstone ileus diagnosed recently in our hospital. A 54 year old elderly female presented with sudden onset abdominal pain with recurrent vomiting for one day. A Plain radiograph of abdomen done in Emergency department suggested findings of small bowel obstruction. It was followed by an urgent ultrasound of abdomen which showed collapsed Gall bladder, pneumobilia and dilated non-peristaltic small bowel loops. Finally a contrast enhanced CT scan of abdomen was done and it showed air within in the biliary tree and within the collapsed Gall bladder. The Small bowel loops were dilated to the upper border of a large radiolucent intraluminal filling defect in the distal ileum. It also showed loss of clear interface between Gall bladder and second part of duodenum suggesting a possibility of Cholecystoenteric fistula. The patient underwent an urgent laparotomy with enterolithotomy. A 35 x 35mm calculus was impacted in the distal ileum. A fistulous communication was noticed between Gall bladder and the second part of duodenum which was repaired along with cholecystectomy.