Evaluation and Comparison of Antioxidant status in ischemic and haemorrhagic cases of stroke

Rahul Kumar Shukla*, B.K. Agrawal, Amit Kumar

Evaluation and Comparison of Antioxidant status in ischemic and haemorrhagic cases of stroke

Rahul Kumar Shukla*, B.K. Agrawal, Amit Kumar

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Rahul Kumar Shukla*, B.K. Agrawal, Amit Kumar, “Evaluation and Comparison of Antioxidant status in ischemic and haemorrhagic cases of stroke”, ijmhs, vol. 10, no. 06, pp. 935–939, Jun. 2020.

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Abstract

Introduction:
The World health organization (WHO) has well-defined stroke as “rapidly progression
of clinical signs of focal and at times global disturbances of cerebral function longlasting
> 24 hours or resulting of death, with no apparent reason other than vascular
region.”
Material and Methods
This case-control study was conducted on an overall population of 200 individuals (58
ischemic strokes and 29 haemorrhagic strokes as the case groups; 58 healthy individuals
as the control group).
Diagnosis: The diagnosis of stroke was based on history and clinical examination and
brain CT scan were used to confirm and classify ischemic and haemorrhagic stroke
cases.
Results:
A total of 200 cases of stroke (58 ischemic stroke, 29 haemorrhagic strokes, and 58
healthy individuals as the control group) were identified during the study follow-up.
GPX levels are reduced significantly in ISPs and HSPs equated with control subjects(
p<0.001). Extreme decrease in GPX is seen in ISPs than HSPs(p<0.001).
Conclusion
Finally, positive direct relationship was seen in MDA along with infarct size. So,
it could consider as a bio marker for recognising stroke. This could be valued for
improving the dose frequency for improvement of patient health. From these studies,
we can conclude that antioxidant defence is reduced in ischemic stroke patients as a
significance of inclined oxidative stress.
Key words: Oxidative stress–Antioxidant–Ischemic–Haemorrhagic

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Innovative Journal of Medical and Health Science

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[1]

Rahul Kumar Shukla*, B.K. Agrawal, Amit Kumar, “Evaluation and Comparison of Antioxidant status in ischemic and haemorrhagic cases of stroke”, ijmhs, vol. 10, no. 06, pp. 935–939, Jun. 2020.

Issue Vol. 10 No. 06 (2020): Innovative Journal of Medical and Health Science
Section Research Articles

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Innovative Journal of Medical and Health Sciences

Evaluation and Comparison of Antioxidant status in ischemic and haemorrhagic cases of stroke

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