##submission.abstract##
The incidence of diabetes mellitus has increased drastically in the last decade globally. The prevalence of diabetes mellitus is significantly high especially in India. Poor socioeconomic status, barefoot walking, lack of hygiene are some of the common reasons for the increasing incidence of infection in diabetic foot ulcers. This study emphasizes the role of garenoxacin in an infected foot ulcer. Staphylococcus aureus is the most common pathogen found to be harboring in such infected ulcers. With superior efficacy and an excellent safety profile garenoxacin can be looked upon as the fluoroquinolone of choice in the treatment of such infections. With once a dosing garenoxacin appears to have improved the compliance in the patients