##submission.abstract##
Introduction : The present study was carried out with objectives to see the efficacy of rectal misoprostol in comparison to intramuscular oxytocin in prevention of postpartum haemorrhage in low risk patient.
Methods: Data of 400 randomly selected obstetric patients who seeked care for delivery at the Obstetrical Units were retrospectively identified. Divided into two groups of A ( Rectal Misoprostol & B of Oxytocin I.M.
Results: No statistical difference among baseline variables , mean duration of labour. The difference in mean blood loss between rectal misoprostol group and oxytocin group is statistically significant. Blood loss during third stage is found to be more in misoprostol group than oxytocin group.
Conclusion : It is observed that the misoprostol rectally is less effective than intramuscular oxytocin when used as prophylactic uterotonic during the active management of third stage of labour. Third stage blood loss found to be significantly more with misoprostol.