Evidenced-based and national context orientated Guidelines help clinicians translate best evidence into best practice. A well-calipered guideline improves quality by reducing variations in healthcare delivery. Clinical Guidelines remarkably contributing to Improving diagnostic accuracy, enhancing effective therapy, and restricting ineffective – or potentially non-effective – interventions. Clinical guidelines methodology seems to be poorly defined and clearly varies at different organizations. One of the gaps needs to be closed under national clinical guidelines is to generate and develop a quality-driven, evidence-based through utilizing an efficient and rigors methodology for action and setting up ready recommendations with multi-disciplinary applicability. The Process of development, that permit moving from conception to completion in a well-defined period of time, always emphasizes a logical sequence of key action statements supported by amplifying text, evidence profiles, as well as a recommendation which link action to evidence.
Sickle cell syndromes pose real public health problems in many African countries also described in the populations of the Mediterranean basin. In Morocco, their frequency and their distribution are poorly known. The objectives of this study are; first, to highlight the epidemiological characteristics second, plot the current mapping of the disease in children under 15 years old of age. A retrospective study was carried out on 86 patients from 01 January to 31 December 2015 at the pediatric department at El Idrissi Regional Hospital Center in Kenitra. The mean age of patient was 7.8 ± 3.1 years; the male sex was the most dominant with 55.81% of patients studied. The SS form represented the majority of cases with 79.07%. Sickle cell anemia remains a reality in our country and not perfectly understood yet by health professionals. A screening policy and a sustainable management program can prevent hemoglobinopathies in our region. An action plan must be implemented at national level to improve the quality of management of main sickle cell syndromes.
a statistical method in order to decode the blood spectrum has been presented. It has been suggested to use AI for decoding FTIR spectra of blood. In this method, there is no requirement to know what the blood samples contain, but only to know what the characteristics of the blood donors are. The principles are that the data is never lost, the phenomena are regular and that the blood spectra contains the donor’s diagnostic information.
In a recent article, Türk et al. reported about a retrospective study of 30 patients with respiratory insufficiency due to diaphragmatic dysfunction having undergone nerve conduction studies of the phrenic nerve or needle electromyography (EMG) of the diaphragm . We have the following comments/concerns. Inclusion criteria are contradictory. Since the study had a retrospective design, the authors knew the diagnosis of all patients, except those with unknown cause, (n=8) in advance. According to the inclusion criteria, those with a known cause of phrenic nerve lesion (n=22) should have been excluded.