POLG1 phenotypes may worsen rather from valproic acid and lidocaine than borreliosis or ceftriaxone

Josef Finsterer, MD, PhD*

POLG1 phenotypes may worsen rather from valproic acid and lidocaine than borreliosis or ceftriaxone

Josef Finsterer, MD, PhD*

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Josef Finsterer, MD, PhD*, “POLG1 phenotypes may worsen rather from valproic acid and lidocaine than borreliosis or ceftriaxone”, ijmhs, vol. 10, no. 06, pp. 924–925, Jun. 2020.

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Abstract

With interest we read the article by Gaudo et al. about
a 3yo female with generalised epilepsy due to the compound
heterozygous variants c.2591A>G and c.3649G>C
in POLG1 [1]. The authors concluded that a concomitant
Borrelia burgdorferi infection and the administration of ceftriaxone
triggered the occurrence of clinical manifestations
of the POLG1 variants and that the antibiotic worsened the
phenotype [1]. The study has several shortcomings.

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Innovative Journal of Medical and Health Science

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[1]

Josef Finsterer, MD, PhD*, “POLG1 phenotypes may worsen rather from valproic acid and lidocaine than borreliosis or ceftriaxone”, ijmhs, vol. 10, no. 06, pp. 924–925, Jun. 2020.

Issue Vol. 10 No. 06 (2020): Innovative Journal of Medical and Health Science
Section Research Articles

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Innovative Journal of Medical and Health Sciences

POLG1 phenotypes may worsen rather from valproic acid and lidocaine than borreliosis or ceftriaxone

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